Pseudomyxoma Peritonei
Pseudomyxoma peritonei (PMP) usually begins as a small polyp-like growth, called an adenoma. It starts in the appendix. Over time, this adenoma breaks through the wall of the appendix and spreads tumour cells to the lining of the abdominal cavity (the peritoneum). These cells produce mucus, which then collects in the abdomen as a jelly-like fluid called mucin.
Unlike other cancers, Pseudomyxoma peritonei very rarely spreads via the lymphatic system or the bloodstream. It usually remains inside the abdomen, spreading along its internal surfaces. The mucus collects in the peritoneum and causes symptoms. It can be many years before symptoms from this type of cancer become obvious.
Most people don’t have any symptoms for a long time. When symptoms occur they may include any of the following:
- slow increase in waist size
- hernia (a swelling on the abdomen)
- loss of appetite
- unexplained weight gain
- abdominal or pelvic pain
- changes in bowel habits
- appendicitis.
Most people with these symptoms won't have Pseudomyxoma peritonei however, it's important to have any symptoms checked by your doctor.
You may be offered surgery to treat this kind of cancer. There are two types of surgery:
- debulking surgery
- complete tumour removal with heated intraperitoneal chemotherapy ( HIPEC ).